Titlebook: Comparative Molecular Neurobiology; Yves Pichon Book 1993 Birkhäuser Verlag 1993 conservation.evolution.membrane proteins.molecular biolog

笼子

Muscarinic acetylcholine receptors in invertebrates: Comparisons with homologous receptors from vertertebrate muscarinic acetylcholine receptors. Evidence for the existence of multiple receptor subtypes in invertebrates is examined, emphasizing what is presently known about the sensitivity of invertebrate preparations to subtype selective ligands previously defined in vertebrate studies. Other evi

健忘症

Pharmacology of the GABA receptor of insect central neurones in culture: A patch-clamp studyhannel techniques. The insect GABA receptor mediated an increase in chloride conductance, which was blocked by picrotoxin but was insensitive to bicuculline. The vertebrate GABA. agonists isoguvacine, muscimol and ZAPA were potent agonists of the insect GABA receptor but the sulphonic acids 3-amino

PANG

GABA Receptor molecules of insectsuch of the information derived from physiological and biochemical studies on insect GABA receptors relates to GABA-gated chloride channels that show some similarities with vertebrate GABA. receptors. Like, their vertebrate central nervous system (CNS) counterparts, agonist activation of such insect

Catheter

Cloning of a putative GABA, receptor from cyclodiene-resistant ,: A case study in the use of insectiroreceptors. Isolation of mutants from the field, mapping of the single gene responsible and its subsequent cloning are described. As confirmation of gene cloning a susceptible allele of the gene has been used to genetically transform resistant individuals to susceptibility. The gene product appears

出生

Molecular biology of excitatory amino acid receptors: Subtypes and subunitsd .-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA). The pharmacology of the NMDA receptor is clearly different from that of the kainate, quisqualate and AMPA receptors, thus differentiating two types: NMDA and non-NMDA receptors. Molecular cloning and expression of non-NMDA receptor subunits

Saline

Molecular analysis of , glutamate receptorsthe well-studied effects of L-glutamate on invertebrate muscle cells, relatively little is known about the physiological role of glutamate receptors (GluRs) in the invertebrate central nervous system. We have applied a molecular cloning approach to elucidate the molecular structure of neuronal and m

incredulity

fiscal

Single channel properties at the synaptic sitew-noise whole cell recordings. The technique of nonstationary fluctuation analysis, which has previously been applied to sodium currents, was modified so that fluctuations were measured around the least-squares scaled fit of the ensemble average to individual synaptic currents. This had the effect o

无弹性

Structural and functional conservation of serotonin receptors throughout evolutionalso in molluscs and arthropodes. Most of these receptors belong to the G protein-coupled receptor family and modulate levels of second messengers such as cAMP, IP. and calcium..Rather than being specialized in a particular physiological function, a given receptor may be expressed in multiple neuron

极深

The wide range of actions of the FMRFamide-related peptides and the biological importance of peptideengers and that they have come to exert a wide range of actions. Using as an example the FMRFamide (Phe-Met-Arg-Phe-NH.) related peptide family of molluscs, the wide range of peptide actions on membrane currents is discussed and considered in relation to co-localization of peptides with low molecula