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Titlebook: Combination Therapies; Biological Response Allan L. Goldstein,Enrico Garaci Book 1992 Plenum Publishing Corporation 1992 AIDS.gene therapy

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发表于 2025-3-21 16:11:12 | 显示全部楼层 |阅读模式
书目名称Combination Therapies
副标题Biological Response
编辑Allan L. Goldstein,Enrico Garaci
视频videohttp://file.papertrans.cn/230/229857/229857.mp4
图书封面Titlebook: Combination Therapies; Biological Response  Allan L. Goldstein,Enrico Garaci Book 1992 Plenum Publishing Corporation 1992 AIDS.gene therapy
描述Over the past decade many of the key lymphokines, hormones and growth factors that help regulate the immune system have been defined. These molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases. Advances in this area have also led to rethinking therapies against a range of autoimmune disorders and other diseases associated with immune and endocrine imbalances. BRMs currently are being applied clinically as both primary and adjunctive therapy to enhance the effectiveness of traditional treatments by maximizing their activities and to protect critical tissues against intolerable chemotherapeutic and radiation damage. Present constraints against the use of BRMs revolve around the nature of these substances in vivo, where many of their actions and the majority of their interactions and synergies remain to be elucidated. For example, as these molecules are thought to exert their effects locally, the systemic administration of lymphokines, cytokines and gro
出版日期Book 1992
关键词AIDS; gene therapy; infections; infectious disease; therapy
版次1
doihttps://doi.org/10.1007/978-1-4615-3340-5
isbn_softcover978-1-4613-6472-6
isbn_ebook978-1-4615-3340-5
copyrightPlenum Publishing Corporation 1992
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Variables Influencing the Sintering of MgOr developing combination chemotherapy regimens, such as increasing dose intensity and combining drugs that have independent antitumor activity, may not apply to those for combining BRMs and cytotoxic drugs. Thus, the rationale for adding BRMs to chemotherapy may be more complex than for combining chemotherapy drugs.
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https://doi.org/10.1007/978-3-322-87843-4an estimated six to ten million HIV-1 infected individuals worldwide and over 160,000 known cases of AIDS in the United States, it is extremely important and urgent to look for strategies to control the disease by antiviral therapy.
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Bekannte Eigenschaften des Nickelaluminids,stein’s laboratory looked at cyclooxygenase inhibitors, among other agents, to determine whether they might influence or inhibit thymic peptides. These studies demonstrated that acetyl salicylic acid (aspirin) could enhance immune responses and synergize with thymosins.
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molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases. Advances i
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https://doi.org/10.1007/978-1-4615-8999-0h advanced local or distant disease. Approximately two-thirds of the all locally confined renal tumors are found incidentally (1). Surgical extirpation is the cornerstone of therapy of localized RCC. In spite of years of research and many clinical trials, the management of metastatic disease remains undefined.
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Combinations of Lymphocyte Activating Agents for Expansion of Tumor Infiltrating Lymphocytes from Reotherapy consisting of infusions of the lymphokine Interleukin-2 (IL-2) or IL-2 combined with Lymphokine Activated Killer (LAK) cells (1, 2). Although some patients responded well to these treatments, the overall rate of anti-tumor responses was relatively low (15–30%) and the therapy was limited by dose-dependent IL-2 toxicity.
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