书目名称 | Cohesin and Condensin |
副标题 | Methods and Protocol |
编辑 | Kyoko Yokomori,Katsuhiko Shirahige |
视频video | http://file.papertrans.cn/230/229233/229233.mp4 |
概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .The volume provides comprehensive, state-of-the-art experimental techniques that are now available to dissect the molecular mechanisms of regulation and function of cohesin and the related factor condensin in vitro and in vivo across different model organisms, as well as in human cells. .Cohesin and Condensin: Methods and Protocols .is divided into three parts: Part I explores various in vitro and in vivo systems used to study the fundamental mechanism of cohesin regulation in mitosis and meiosis; Part II summarizes experimental systems in a variety of organisms that are used to address interphase functions of cohesin and Nipbl in gene regulation and chromatin interaction, ribosome biogenesis and DNA repair, which contribute significantly to cohesion-associated disorders; Part III covers related condensin complex and describes techniques to study its role in mitosis and interphase. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Cutti |
出版日期 | Book 2017 |
关键词 | cohesin regulation; cell-free system in Xenopus; cohesin-dependent sister chromatid cohesion; loading f |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4939-6545-8 |
isbn_softcover | 978-1-4939-8232-5 |
isbn_ebook | 978-1-4939-6545-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media New York 2017 |