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Titlebook: Clinical Use of Calcium Channel Antagonist Drugs; Lionel H. Opie,William A. Coetzee Book 1989 Kluwer Academic Publishers, Boston 1989 angi

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书目名称Clinical Use of Calcium Channel Antagonist Drugs
编辑Lionel H. Opie,William A. Coetzee
视频videohttp://file.papertrans.cn/229/228284/228284.mp4
图书封面Titlebook: Clinical Use of Calcium Channel Antagonist Drugs;  Lionel H. Opie,William A. Coetzee Book 1989 Kluwer Academic Publishers, Boston 1989 angi
描述Calcium antagonists are now regarded as the most important advance in cardiac drug therapy since the advent of beta-adrenergic blocking agents. Acting ba­ sically as vasodilators-though with many other com­ plex mechanisms especially in the case of the anti­ arrhythmic calcium antagonists, these agents have grown in importance to become among the therapeutic agents of first choice for angina pectoris and hyper­ tension. The major aim of the present book is to present the clinician with the information needed for the practical use of calcium antagonists. What do all the numerous and often conflicting trials say? Do these agents really work? If so, which agent and in what dose? How do the three front runners, verapamil, nifedipine and diltia­ zem compare in the efficacy and side-effects with each other? How do the new second generation agents, now entering the North American market, slot in and com­ pare with the three first-liners? When the gloss is taken away from the advertisements, what is really left? The strong clinical bias of the present book should be complimented by further reading of books slanted towards fundamentals. One of the most important and recent of these is that
出版日期Book 1989
关键词angina pectoris; arrhythmia; calcium; drug; drugs; heart; heart disease; hypertension; therapy
版次1
doihttps://doi.org/10.1007/978-1-4613-0863-8
isbn_softcover978-1-4612-8208-2
isbn_ebook978-1-4613-0863-8
copyrightKluwer Academic Publishers, Boston 1989
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https://doi.org/10.1007/978-1-4842-4810-2s of existing agents include slow-release formulations of nifedipine, verapamil, and diltiazem. From all these agents will be selected those that are longer-acting and provide higher vascular selectivity.
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Clinical Pharmacokinetics of First and Second-Generation Agents,lcium antagonists. There are also other potential drug interactions of a kinetic or dynamic nature that may arise. In general, renal disease has little effect on the pharmacokinetics of calcium antagonists.
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Use and Comparative Efficacy in Hypertension and Supraventricular Arrhythmias. Minor Indications,eft ventricular hypertrophy or renal insufficiency. However, the goal blood pressure may not be reached during monotherapy so that drug combinations may be required. Further indications for these compounds are as follows. Verapamil and diltiazem are frequently used in supraventricular tachycardias i
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