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Titlebook: Clinical Trials in ‘Early’ Breast Cancer; Methodological and C H. R. Scheurlen,G. Weckesser,I. Armbruster Conference proceedings 1979 Sprin

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Satellitenortung und Navigationnt based on axillary node histology with a standard radical policy of treatment in patients with primary breast cancer.(1,2) Although the surgical policy under test was a simple mastectomy, node histology was considered essential as clinical staging of the axilla is known to be inaccurate. (3)
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https://doi.org/10.1007/b139118ays unsatisfactory however perfectly they may have seemed to be taken away. The reason of this probably is that the glands do not participate in the disease unless the system is strongly disposed to it”. It has taken us well over a hundred years to rediscover this fundamental truth concerning the bi
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Orbit Relative to the Sun. Crossing Times,on (RT), has been critically re-evaluated during the past few years. The analysis of prospective controlled studies (4,6) has clearly indicated the limits of treatment based only on anatomical principles (5). Furthermore, the histological status of axillary lymph nodes has proved to be the single mo
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https://doi.org/10.1007/b139118postoperative X-ray irradiation (McWhirters method) and extended radical mastectomy (Dahl-Iversen’s method) (1). A comparison of the two methods showed the same survival as well as recurrence-free survival up to 15 years for operable cases as a whole as well as for clinical stage I and for clinical
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https://doi.org/10.1007/b139118viations. When reporting the results of such trials the patients who had not been treated according to the protocol sometimes were excluded from the analyses, assuming that the reasons for the deviations from treatment were not of a nature which could bias the results.
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https://doi.org/10.1007/b139118. Hazard models are discussed and the construction of the likelihood is reviewed with special attention being paid to the role of censoring schemes and time varying covariates. These covariates are classified as controlled, ancillary and internal covariates and some of their uses are discussed. This
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