Titlebook: Clinical Trials in Neurology; Felipe Fregni Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018 Stroke.Parkinsons

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Peripheral Neuropathy, its high incidence and the great number of challenges faced by researchers in this field, this chapter provides an extensive discussion of the 100 most cited clinical trials between 2005 and 2015. A systematic review was performed, based on the CONSORT guidelines, by analyzing Web of Science databa

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Epilepsy,on such trials. A literature search on “epilepsy” was performed using Web of Science, and the top 100 cited articles on interventional clinical trials in epilepsy between 2010 and 2015 were analyzed and used to provide guidance to future investigators. Based on CONSORT guidelines for reporting clini

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Future of Clinical Trials in Neurology, conditions, with the aim of providing future perspectives for the development of high-quality clinical trials in neurology. Therefore, the limitations of the studies are discussed, possible solutions as well as the areas in which research is still needed. For this purpose, relevant practices in the

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Introduction,uch as study population, trial outcomes, design, statistical analysis, and ethical aspects are contemplated in this chapter. As the neurology field is the focus of this book, practical examples on neurological disorders are also discussed.

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Dystonia,ence,” searching for the 100 most cited trials in Dystonia, published between 2005 and 2015. This chapter discusses the findings of this review and provides recommendations for augmenting future research studies in the field.

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,Alzheimer’s Disease,ence. Based on the guidelines by the CONSORT group and the criteria contained in them, relevant practices in these clinical trials are discussed and suggestions are made for the improvement on the design and conduction of further clinical studies in the field.

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,Tumors of the Central Nervous System, 90 most cited articles in this field were included in the review. Important methodological aspects of these trials are deeply explored in this chapter with the goal of improving the conduction of future research studies.

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Spinal Cord Injury, order to collect the data of the 110 most cited articles in SCI for the last 10 years. A detailed discussion based on the criteria of the consort guidelines is provided with the most common findings as well as suggestions for the improvement on the design of future SCI clinical trials.

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Epilepsy,cal trials, we discuss relevant findings in detail, showing the methods used to design various types of interventional epilepsy trials. We make recommendations on best practice methods in epilepsy trial design.