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Titlebook: Clinical Metabolomics; Methods and Protocol Martin Giera Book 2018 Springer Science+Business Media, LLC 2018 Liquid chromatography–mass spe

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发表于 2025-3-21 18:16:21 | 显示全部楼层 |阅读模式
书目名称Clinical Metabolomics
副标题Methods and Protocol
编辑Martin Giera
视频video
概述Includes cutting-edge methods and protocols for the use of clinical metabolomics.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the e
丛书名称Methods in Molecular Biology
图书封面Titlebook: Clinical Metabolomics; Methods and Protocol Martin Giera Book 2018 Springer Science+Business Media, LLC 2018 Liquid chromatography–mass spe
描述This detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. The methodologies explored here form the core of several very promising initiatives evolving around personalized health care and precision medicine, which can be seen as complimentary to the field of clinical chemistry and aid the aforementioned field with novel disease markers and diagnostic patterns. Written for the highly successful .Methods in Molecular Biology. series, chapters include brief introductions to their topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Clinical Metabolomics: Methods and Protocols .aims to serve as the basis for successful communication between scientists from several fields, including chemists, biologist, bioinformaticians, and clinicians, ultimately leading to effective study design and completion..
出版日期Book 2018
关键词Liquid chromatography–mass spectrometry; Clinical chemistry; Personalized health care; Precision medici
版次1
doihttps://doi.org/10.1007/978-1-4939-7592-1
isbn_softcover978-1-4939-8530-2
isbn_ebook978-1-4939-7592-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC 2018
The information of publication is updating

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Metabolomics in Immunology Researchroles in the outcome of immune responses. In this respect, the use of MS- and NMR spectroscopy-based platforms to characterize and quantify metabolites in biological samples has recently yielded important novel insights into how our immune system functions and has contributed to the identification o
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LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples autoxidation. Insofar it has been marked as novel biomarkers of oxidative stress in the biological systems. Elevations of these oxidized products are associated with several diseases. This chapter describes the preparation and measurement of the products, including newly identified F.-dihomo-isopro
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Serum Testosterone by Liquid Chromatography Tandem Mass Spectrometry for Routine Clinical Diagnosticies. For these samples, sensitive and specific LC-MS/MS-based testosterone methods are required. An LC-MS/MS-based testosterone assay is described that was developed and validated for routine clinical application.
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LC-MS/MS Analysis of Bile Acidsrs and nuclear hormone receptors. So they control their own metabolism and act on lipid and energy metabolism. Here we describe a simple, accurate, and fast liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of BAs in human plasma/serum.
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LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl EthanolamiWe report a LC-MS/MS method developed specifically to analyze CYP products of the arachidonoyl ethanolamide (anandamide, AEA), the epoxyeicosatrienoic acid ethanolamides (EET-EAs) and their hydrolyzed metabolites, and the dihydroxyeicosatrienoic acid ethanolamides (DHET-EAs). This method was used to
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