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Titlebook: Clinical Applications of Mass Spectrometry in Drug Analysis; Methods and Protocol Uttam Garg Book 2024Latest edition The Children�s Mercy H

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Untargeted High-Resolution Mass Spectrometry for Detection of Natural Products and Confiscated Powdpropriate), in order to obtain and test the drugs, plants, herbals, or chemicals that were taken. Methods are needed for the extraction, purification, and untargeted mass spectral analysis of drugs from the donated or seized materials.
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https://doi.org/10.1007/3-7908-1668-Xecialized clinical laboratories for decades. In clinical laboratories, it is used for compound identification and quantification. Due to the ability to provide specific identification, high sensitivity, and simultaneous analysis of multiple analytes (>100) in recent years, application of MS in routi
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https://doi.org/10.1007/3-7908-1668-Xpregabalin (PRG), rufinamide (RFM), and vigabatrin (VGB) have been approved and marketed since 1989. Accurate measurement of serum concentration of the antiepileptic drugs is crucial to achieve optimal efficacy and avoid adverse events. We describe an accurate and precise liquid chromatography-tande
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Developments in Cardiovascular Medicine(AED) can help control the incidence of epileptic seizures. AED therapeutic regimens often need to be individually tailored. Therapeutic drug monitoring (TDM) of AED is required to optimize therapeutic efficacy and minimize the risk of any associated destructive toxicities. We describe a turbulent f
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Developments in Cardiovascular MedicineEDs can be used as single agents but are commonly administered in combination, as a multi-drug regimen. AEDs have narrow therapeutic windows. Therapeutic ranges may not be properly defined, and symptoms of toxic serum concentrations may include increased frequency of seizures, as seen when AED conce
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Developments in Cardiovascular Medicineections in acute myeloid leukemia (AML) patients after receiving hematopoietic stem cell transplantation (HSCT). Recent studies have shown that atovaquone has shown potential as an anticancer agent. The high variability in atovaquone bioavailability prompts the need for therapeutic drug monitoring,
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