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Titlebook: Circulating Tumor Cells; Richard J. Cote,Ram H. Datar Book 20161st edition Springer Science+Business Media, LLC, part of Springer Nature 2

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书目名称Circulating Tumor Cells
编辑Richard J. Cote,Ram H. Datar
视频videohttp://file.papertrans.cn/227/226644/226644.mp4
概述Provides a blueprint on how circulating tumor cells can be employed in the future.Features authors from diverse backgrounds in biology, biochemistry, and medical oncology?.Delivers a “one-stop” text t
丛书名称Current Cancer Research
图书封面Titlebook: Circulating Tumor Cells;  Richard J. Cote,Ram H. Datar Book 20161st edition Springer Science+Business Media, LLC, part of Springer Nature 2
描述This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers..CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive “liquid biopsy” procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development. In recent years there has been rapid growth and worldwide developments on CTCs, which span both the basic sciences and biomedical engineering fields..
出版日期Book 20161st edition
关键词biomarker; cancer; ctc; metastasis; tumor
版次1
doihttps://doi.org/10.1007/978-1-4939-3363-1
isbn_softcover978-1-4939-8031-4
isbn_ebook978-1-4939-3363-1Series ISSN 2199-2584 Series E-ISSN 2199-2592
issn_series 2199-2584
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2016
The information of publication is updating

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K. Purvis,M. Parvinen,K. Gautvik,V. Hanssone CTC from cancer patients’ peripheral blood—the affinity-based enrichment of CTC. We briefly discuss the different technologies utilizing antibodies to capture CTC based on specific antigen expression. Then we address the downstream molecular and functional characterization of CTC by utilizing thes
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Max H. Schreier,Theophil Staehelinancer management (Cristofanilli et al., N Engl J Med 351(8):781–791, 2004; Cohen et al., J Clin Oncol 26(19):3213–3221, 2008; de Bono et al., Clin Cancer Res, 14(19):6302–6309, 2008; Poveda et al., Gynecol Oncol, 122(3):567–572, 2011). However, the technical hurdle for studying CTCs is their rare pr
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https://doi.org/10.1007/978-1-4615-1651-4ls” (CSCs). These cells have the ability to self-renew and to generate heterogeneous populations that constitute the tumor bulk. Preclinical studies have demonstrated that CSCs mediate tumor metastasis and resistance to chemotherapy and radiation therapy. CSC biomarkers have been identified and both
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Helge Großhans,Saibal Chatterjeecer recurrence remain poorly understood, failure to completely eliminate dormant micrometastases and solitary metastatic cells is believed to be a major contributor. Thus, while not of initial clinical concern, metastatic dormancy is still a significant clinical problem. The emerging use of circulat
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https://doi.org/10.1007/978-4-431-65880-1ire the morphology of solitary migratory cells, has been implicated in the progression of carcinoma. EMT may contribute to the formation of cancer stem cells, evasion of immune surveillance, and induction of resistance to chemotherapeutics and targeted therapeutics. Metastasis is governed by a compl
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