| 书目名称 | Circadian Pharmacokinetics | | 编辑 | Baojian Wu,Danyi Lu,Dong Dong | | 视频video | | | 概述 | Reinforces basic knowledge and principles on circadian clock and metabolic diseases.Enriches understanding of circadian regulation of drug metabolism and transport.Serves as a helpful reference and pr | | 图书封面 |  | | 描述 | This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book‘s contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book. | | 出版日期 | Book 2020 | | 关键词 | Pharmacokinetics; Circadian clock; Drug-metabolizing enzymes; Uptake and efflux transporters; Chronother | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-15-8807-5 | | isbn_softcover | 978-981-15-8809-9 | | isbn_ebook | 978-981-15-8807-5 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
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发表于 2025-3-21 19:25:07
