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Titlebook: Chronic Myeloid Leukemia; Methods and Protocol Shaoguang Li,Haojian Zhang Book 2016 Springer Science+Business Media New York 2016 Cancer st

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Panja Schweder,Phil C. Langer,Angela Kühnerluable in detecting and characterizing genome-wide miRNAs of either too high or too low abundance. Besides, it can also be used in detecting novel miRNAs. Here, we describe an ab initio analysis of an example chronic myeloid leukemia miRNA sequencing data set to quantify the global expression of miR
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https://doi.org/10.1007/978-3-658-03112-1involvement of miRNA and their targets in CML stem cells self-renewal, maintenance, and therapeutic resistance. Here, we describe a simplified integrative analysis using Ingenuity Pathway Analysis software after performing proper RNA extraction, miRNA and mRNA microarray and data analysis.
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https://doi.org/10.1007/978-3-658-12932-3ogenesis and evaluate therapeutic drugs in the past three decades. Here, we describe the procedures to generate a CML mouse model by introducing . into Lin.Sca1. cKit. population cells purified from mouse bone marrow. In CML retroviral transduction/transplantation mouse models, this modified model can mimic CML pathogenesis on high fidelity.
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