Titlebook: Chromosomes Today; Volume 12 N. Henriques-Gil,J. S. Parker (Professor of Plant Book 1997 Springer Science+Business Media Dordrecht 1997 Ch

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Characterization of amplified DNA sequences in human cancersprovides means to increase the copy number of certain DNA sequences during a single cell cycle. Submicroscopic circular molecules, called episomes, were found in cells with amplified genes and might represent precursors of dmin (Carroll ., 1988; Van Hoff ., 1988; Wahl, 1989).

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