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Titlebook: Chromosomes Today; Volume 8 Proceedings M. D. Bennett,A. Gropp,U. Wolf Conference proceedings 1984 The Organising Committee of the VIII Int

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Paul Hoyningen-Huene,Franz M. Wuketitsaining one balanced genome. In eukaryotes pairing between homologous chromosomes or chromosome segments is mediated by the synaptonemal complex, which ensures that the homologous segments are held in register for a certain period of time — the pachytene stage (Westergaard and von Wettstein 1972). At
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https://doi.org/10.1007/978-3-642-99551-4nisms involved remains so inadequate. Probably no other aspect of human aneuploidy has attracted more attention over the years than the aetiology, and yet the cause of Down’s syndrome still eludes us and the factors underlying the maternal age effect remain obscure.
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