Titlebook: Chromosome 12 Aberrations in Human Solid Tumors; Cytogenetics and Mol J. Bullerdiek,S. Bartnitzke Conference proceedings 1994 Springer-Verl

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Development and Characterization of Cell Lines from a Myxoid Liposarcoma with t(12;16)(q13;p11.2) antween chromosomes 12 and 16, t(12;16)(q13;p11), or a three-way translocation also involving chromosome 1 (Turc-Carel et al. 1986a; Ohjimi et al. 1992). Interestingly, in cytogenetically abnormal lipomas the same cytogenetic region of chromosome 12 is frequently implicated in translocations; in contr

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Analysis of Solid Tumours with Recurrent Breakpoints in Chromosome Region 12q13–15 by Fluorescence Is et al. 1991) and pleomorphic adenomas of the salivary gland (Sandros et al. 1990). Comparison of available cytogenetic data suggests that the chromosome 12 breakpoint in myxoid liposarcoma is proximal to those in the three benign tumours; this might point towards the implication of different genet

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Permanent

Involvement of Chromosome 12 in Uterine Leiomyomae, and very rarely below the age of 18. Their pathogenesis is not clearly understood, but a role for sex steroid hormones is likely since they increase in size during pregnancy or after administration of oral contraceptives (Buttramn and Reiter 1981) and regress after menopause and under luteinizing

refraction

Lipoma Cytogenetics). It should, however, be stressed that the data are heavily biased in favor of hematologic neoplasms; of the total data base comprising 14141 human tumors reported to have clonal chromosome aberrations, 68% involve hematologic disorders, 11%, lymphomas, and 21%, solid tumors (Mitelman 1991). This i

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Breakpoints and Recipient Chromosomes in Pleomorphic Adenomas, Lipomas, and Uterine Leiomyomas — Whang 12q13–15. The currently best investigated examples are pleomorphic adenomas (Mark et al. 1980, 1988; Bullerdiek et al. 1987a,b), lipomas (Heim et al. 1986; Turc-Carel et al. 1986a; Mandahl et al. 1988), myxoid liposarcomas (Turc-Carel et al. 1986b), and uterine leiomyomas (Heim et al. 1988; Turc-

myocardium

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Cytogenetic and Molecular Studies of Clear-Cell Sarcoma of Tendons and Aponeurosest clinicopathologic entity among soft tissue sarcomas. Originally it was suspected that there was a relationship between CCS and synovial sarcoma (Enzinger 1965; Kubo 1969; Hajdu et al. 1977). The light-microscopic similarity to malignant melanoma, the occurrence of melanin in some cases (Enzinger 1