| 书目名称 | Chromatin Remodeling | | 副标题 | Methods and Protocol | | 编辑 | Randall H. Morse | | 视频video | | | 概述 | Features a wide range of methods, including in vitro, in vivo, visual, molecular, genomic, and computational.Authored by recognized leaders in the field of chromatin biology.Includes expert tips and i | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .Chromatin is of central importance to gene regulation in eukaryotes. Reflecting this singular role for chromatin, numerous approaches have evolved in the laboratory over the past three decades to study chromatin structure and its alterations. Methods of investigating chromatin remodeling, whether in changes in nucleosome structure or position with respect to the incorporated DNA or in histone modifications, have progressed rapidly over the recent years. In .Chromatin Remodeling: Methods and Protocols., expert researchers contribute chapters which include methods for investigating chromatin remodeling in vitro and in vivo, in yeast, plants, and mammalian cells, and at local and global levels. Both gene-specific and genome-wide approaches are covered, and in recognition of the increasing prevalence of the latter type of study, the final two chapters focus on bioinformatic/computational approaches to analyzing genome-wide data on chromatin structure. Written in the highly successful .Methods in Molecular Biology™. series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laborator | | 出版日期 | Book 2012 | | 关键词 | Chromatin; Developmental biology; Epigenetics & epigenomics; Gene regulation; Genome-wide data; Histones; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-61779-477-3 | | isbn_softcover | 978-1-4939-6213-6 | | isbn_ebook | 978-1-61779-477-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC 2012 |
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发表于 2025-3-21 18:22:14
