| 书目名称 | Chromatin Regulation of Early Embryonic Lineage Specification |
| 编辑 | Jason Knott,Keith Latham |
| 视频video | |
| 概述 | Examines the roles of early acting chromatin regulators in ICM and TE formation.Explores the role of RHOA subfamily of small GTPases and RHO-associated coiled-coil kinases.Provides an overview on the |
| 丛书名称 | Advances in Anatomy, Embryology and Cell Biology |
| 图书封面 |  |
| 描述 | .Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the pluripotent inner cell mass (ICM) and extraembryonic trophectoderm (TE). The second cell-fate choice encompasses the transformation of ICM into extraembryonic primitive endoderm (PE) and pluripotent epiblast. The processes, which occur during the period of preimplantation development, serve as the foundation for subsequent developmental events such as implantation, placentation, and gastrulation. The mechanisms that regulate them are complex and involve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages. . |
| 出版日期 | Book 2018 |
| 关键词 | extraembryonic primitive endoderm; pluripotent epiblast; embryonic chromatin structure; CHD1; CHD4; H3R26 |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-63187-5 |
| isbn_softcover | 978-3-319-63186-8 |
| isbn_ebook | 978-3-319-63187-5Series ISSN 0301-5556 Series E-ISSN 2192-7065 |
| issn_series | 0301-5556 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 19:25:25
