Titlebook: Chromatin Regulation of Early Embryonic Lineage Specification; Jason Knott,Keith Latham Book 2018 The Editor(s) (if applicable) and The Au

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Introduction,olve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages.

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0301-5556 -associated coiled-coil kinases.Provides an overview on the .Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision inv

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978-3-319-63186-8The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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Reconstructive Microvascular Surgery placenta. At some point, the embryo produces enough cells that some are located on the outside of the embryo, while others are completely surrounded by other cells. It is at this point that cells undergo the very first lineage commitment event: outer cells form the trophectoderm and lose the potent

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Reconstructive Microvascular Surgeryns. The very first of these is lineage specification into the inner cell mass (ICM) and trophectoderm (TE) during mammalian preimplantation development. In mouse embryos, transcription factors (TFs) such as Oct4, Sox2, and Nanog are enriched in cells of ICM, which gives rise to the fetus and yolk sa

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