| 书目名称 | Chromatin Architecture | | 副标题 | Advances From High-r | | 编辑 | Kirti Prakash | | 视频video | http://file.papertrans.cn/227/226295/226295.mp4 | | 概述 | Nominated as an outstanding PhD thesis by the Institute of Molecular Biology, Mainz, and Heidelberg University, Germany.Provides a pictorial description of super-resolution microscopy and chromatin ar | | 丛书名称 | Springer Theses | | 图书封面 |  | | 描述 | .This book sheds new light on the current state of knowledge concerning chromatin organization. Particular emphasis is given to the new imaging potential offered by super-resolution microscopy, which allows DNA imaging with a very high labeling density..From the early work on chromosomes by Walther Flemming in the nineteenth century to recent advances in genomics, the history of chromatin research now spans more than a century. The various milestones, such as the discovery of the double helix structure, the sequencing of the human genome, and the recent description of the genome in 3D space, show that understanding chromatin and chromosome function requires a clear understanding of its structure..Presenting cutting-edge data from super-resolution single molecule microscopy, the book demonstrates that chromatin manifests several levels of folding, from nucleosomes to chromosomes. Chromatin domains emerge as a new fundamental building block of chromatin architecture, with functions possibly related to gene regulation..A detailed description of chromatin folding in the pachytene stage of meiosis serves as a model for exploring this functionality, showing the apparent interplay between | | 出版日期 | Book 2017 | | 关键词 | Superresolution Microscopy; Single Molecule Localisation Microscopy; Genome Architecture; Chromatin Dom | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-52183-1 | | isbn_softcover | 978-3-319-84841-9 | | isbn_ebook | 978-3-319-52183-1Series ISSN 2190-5053 Series E-ISSN 2190-5061 | | issn_series | 2190-5053 | | copyright | Springer International Publishing AG 2017 |
The information of publication is updating
|
|
|Archiver|手机版|小黑屋|
派博传思国际
( 京公网安备110108008328)
GMT+8, 2025-8-25 13:18
发表于 2025-3-21 20:05:31
