书目名称 | Cholesterol Modulation of Protein Function |
副标题 | Sterol Specificity a |
编辑 | Avia Rosenhouse-Dantsker,Anna N. Bukiya |
视频video | http://file.papertrans.cn/227/226160/226160.mp4 |
概述 | Very timely topic as cholesterol, increasingly, has been implicated as a major regulator of protein function.Contributors are well-known experts in their fields and provide international perspective.R |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | .In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. .This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function. . The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in t |
出版日期 | Book 2019 |
关键词 | cholesterol modulation; protein function; membrane cholesterol; lipid sensors; cholesterol distribution; |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-030-04278-3 |
isbn_ebook | 978-3-030-04278-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |