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Titlebook: Cholecystokinin Antagonists in Gastroenterology; Basic and Clinical S Guido Adler,Christoph Beglinger Book 1991 Springer-Verlag Berlin Heid

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书目名称Cholecystokinin Antagonists in Gastroenterology
副标题Basic and Clinical S
编辑Guido Adler,Christoph Beglinger
视频video
图书封面Titlebook: Cholecystokinin Antagonists in Gastroenterology; Basic and Clinical S Guido Adler,Christoph Beglinger Book 1991 Springer-Verlag Berlin Heid
描述A new presentation of physiological regulatory mechanisms and therapeutic applications is given in this book. It represents a collection of the most up-to-date information in cholecystokinin (CCK) research, especially focusing on the development and characterization of CCK antagonists. The book contains chapters on the synthesis, biochemical and pharmacological characterization of potent and selective CCK antagonists as well as physiological applications of these compounds. The last section of the book is devoted to the involvement of CCK in pathological states and potential clinical applications of CCK antagonists.
出版日期Book 1991
关键词CCK-Antagonisten; Darm; Gastrointesinaltrakt; Magen; Magendarmkrankheit; cck-antagonists; gastroenterology
版次1
doihttps://doi.org/10.1007/978-3-642-76362-5
isbn_softcover978-3-642-76364-9
isbn_ebook978-3-642-76362-5
copyrightSpringer-Verlag Berlin Heidelberg 1991
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,Flexible und aufgabenadäquate Rechenwege,During the 1960s at Rotta Research Laboratorium, Rovati [1] developed a gastrin receptor antagonist named proglumide, i.e., .-4-benzamido-., .dipropyl-glutaramic acid. Proglumide has been used for several years for the treatment of peptic ulcer.
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Heterogeneity of CCK Receptors: Classification and CharacterizationReceptors which recognize cholecystokinin (CCK) peptides are particularly interesting and notable, both for their similarities and for their differences. There appear to be a family of such receptors which will likely be homologous, yet possess exquisite differences in their structural specficities.
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Pentanoic Acid DerivativesDuring the 1960s at Rotta Research Laboratorium, Rovati [1] developed a gastrin receptor antagonist named proglumide, i.e., .-4-benzamido-., .dipropyl-glutaramic acid. Proglumide has been used for several years for the treatment of peptic ulcer.
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978-3-642-76364-9Springer-Verlag Berlin Heidelberg 1991
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Pyloric Cholecystokinin Receptorsch these actions may be mediated have been identified in multiple brain regions and at various sites in the gastrointestinal tract. This chapter focuses on the anatomy, pharmacological characterization, and functional significance of a population of CCK receptors localized to the circular muscle layer of the pyloric sphincter.
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