Titlebook: Chirurgisches Forum 2001 für experimentelle und klinische Forschung; 118. Kongreß der Deu K. Schönleben (Präsident des 118. Kongresses der

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Rolle von Appendix und Milz im Mausmodell chronisch entzündlicher Darmerkrankungenal assessment of DSS-treated mice subjected to appendectomy or combined appendectomy/splenectomy exhibited a delayed onset and course of disease activity. Histomorphologic examination revealed significantly lower damage scores and a reduction in ulcerated mucosal surface area. Colonic MPO activity,

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Die Rolle der Apoptose-regulierenden Proteine Bcl-xL und Bax in der durch Gemcitabin induzierten Cyto or only a marginal effect on the apoptotic response of these cells to gemcitabine. These data suggest that Bel-xL, but not Bax, may represent a useful prognostic factor for selecting patients who may benefit from gemcitabine treatment.

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Inhibition von ICE (Caspase-1) induziert Zelltod in Pankreaskarzinomzellenssion levels of the proteins of the bcl-2 family, known to play a key role in the regulation of cell death. . Our observations support our previous findings that ICE may be involved in antiapoptotic processes in pancreatic carcinoma and may provide new aspects in its role in proliferation and cell d

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Anti-angiogenetische Therapie zur Behandlung vom humanen Pankreaskarzinom nach orthotoper Implantatip to 4 weeks. The tumors were then harvested and evaluated for apoptosis, proliferation, NF-КB activity, and angiogenic markers. In vitro analysis of NF-КB activity was done using gel shift techniques, and dual luciferase assays using a NF-КB consensus sequence and a full length VEGF promoter. Treat