| 书目名称 | Chimeric RNA | | 副标题 | Methods and Protocol | | 编辑 | Hui Li,Justin Elfman | | 视频video | | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | This book provides numerous methods for identification, validation, and functional characterization of chimeric RNAs, herein described as any transcript which contains the nucleotide sequence of two distinct parental genes. Beginning with identification and characterization through bioinformatics tools, the book continues with experimental validation using RT-PCR, hybridization methods for RNA, and the use of mass spectrometry data for fusion protein validation, as well as functional and mechanistic studies of chimeric RNAs and translational applications. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Chimeric RNA: Methods and Protocols. is an ideal guide to this expansive field and an inspiration to researchers seeking to further our knowledge of these remarkable features of the transcriptome.. | | 出版日期 | Book 2020 | | 关键词 | Gene fusion; Transcription-mediated fusions; Fusion transcripts; Bioinformatics; Translational applicati | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-9904-0 | | isbn_softcover | 978-1-4939-9906-4 | | isbn_ebook | 978-1-4939-9904-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2020 |
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发表于 2025-3-21 16:16:33
