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Titlebook: Childhood Leukemia: Present Problems and Future Prospects; Proceedings of the S Noboru Kobayashi,Tai Akera,Shuki Mizutani Conference procee

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Quantum Theory of Chemical Reactivityy relevant to the underlying mechanisms of leukemogenesis, the etiology of childhood ALL remains an enigma. A hypothesis is proposed that takes into account geographic and time trend variations in incidence rates, unusual properties of lymphocyte precursors, and promoting effects of immune responses in infancy.
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Quantum Theory of Chemical Reactivityen in coculture of KM cells, and established hematopoietic cells. These results suggest that marrow stromal cells modulate hematopoiesis through the secretion of hematopoietic diffusible factors, direct stromal cell-hematopoietic cell contact, and intercellular gap junctions.
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