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Titlebook: Childhood Acute Lymphoblastic Leukemia; Ajay Vora Book 2017 Springer International Publishing Switzerland 2017 acute lymphoblastic leukemi

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发表于 2025-3-21 17:31:05 | 显示全部楼层 |阅读模式
书目名称Childhood Acute Lymphoblastic Leukemia
编辑Ajay Vora
视频video
概述Exhaustively reviews current therapeutic strategies and applications of precision medicine in ALL treatment.Provides scientists and clinicians with state of the art knowledge to guide their research a
图书封面Titlebook: Childhood Acute Lymphoblastic Leukemia;  Ajay Vora Book 2017 Springer International Publishing Switzerland 2017 acute lymphoblastic leukemi
描述.This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy...Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches.  Supportive care and management of the condition in resource poor countries are also discussed in detail...This is an indispensable guide for  research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia..
出版日期Book 2017
关键词acute lymphoblastic leukemia; pediatrics; hematology; genetics; cytogenetics; immunotherapy; first-line tr
版次1
doihttps://doi.org/10.1007/978-3-319-39708-5
isbn_softcover978-3-319-81947-1
isbn_ebook978-3-319-39708-5
copyrightSpringer International Publishing Switzerland 2017
The information of publication is updating

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https://doi.org/10.1007/978-90-481-8704-1ave a more varied presentation. Bone pain and the signs and symptoms of mediastinal and central nervous system involvement are of particular relevance. Time to presentation for medical attention is related to presenting symptoms. In this chapter, the clinical and laboratory features of ALL at presen
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HwanSuk Chris Choi,Ercan Sirakaya Turkple effector mechanisms of the antileukemic agents that are responsible for the efficacy (Fig. 5.1 and Table 5.1). This contrasts the modern era of targeted therapy, where molecular mapping of chemoresistant cancer cells has led to development of drugs that specifically target aberrant pathways (see
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Filippo M. Denaro,Giuliano De Stefano. MRD measurements have proven to be the strongest independent prognostic factor, allowing for risk-group assignment into different treatment arms, ranging from treatment reduction or intensification. MRD measurements are also guiding treatment decisions in relapsed ALL patients and patients undergo
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Katherine N. Marenco,David J. Bottjergic subsets of childhood ALL and improved clinical risk stratification of patients. These genomic advances have further identified key leukaemia-associated pathways and somatic alterations that may be amenable to therapeutic targeting with kinase inhibitors and other molecularly-targeted agents. Thi
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