Titlebook: Chemotherapy of Viral Infections; Paul E. Came,Lawrence A. Caliguiri Book 1982 Springer-Verlag Berlin Heidelberg 1982 Arzneitherapie.Infec

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Pathogenesis of Viral Infectionsin cell culture) with some information on the course and outcome of infection (insofar as it can be studied) in the whole animal. A comprehensive review of molecular virologic studies would be so diverse that it would be beyond the scope of this chapter and would probably be superfluous for the majo

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Pyrimidine Nucleosides with Selective Antiviral Activity” agents, of which several are pyrimidine nucleosides, can effectively inhibit the replication of herpes simplex viruses with little or no host cell toxicity (Fig. 1). Although the exact mechanisms of action of those compounds may not be fully elucidated, it is clear that their selectivity is depend

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Purinesffective as antiviral agents, and are the only class of antiviral drugs which have ultimately reached the hands of practicing physicians for widespread clinical use against herpesvirus. Although the pyrimidine nucleoside, 5-iodo-2′-deoxyuridine (idoxuridine, IdUrd), was the first of these to do so,

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