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Titlebook: Chemotherapy of Viral Infections; Paul E. Came,Lawrence A. Caliguiri Book 1982 Springer-Verlag Berlin Heidelberg 1982 Arzneitherapie.Infec

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书目名称Chemotherapy of Viral Infections
编辑Paul E. Came,Lawrence A. Caliguiri
视频videohttp://file.papertrans.cn/225/224976/224976.mp4
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Chemotherapy of Viral Infections;  Paul E. Came,Lawrence A. Caliguiri Book 1982 Springer-Verlag Berlin Heidelberg 1982 Arzneitherapie.Infec
描述" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of
出版日期Book 1982
关键词Arzneitherapie; Infections; Viruskrankheit; chemotherapy; immunology; kinetics; pharmacodynamics; pharmacok
版次1
doihttps://doi.org/10.1007/978-3-642-68487-6
isbn_softcover978-3-642-68489-0
isbn_ebook978-3-642-68487-6Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 1982
The information of publication is updating

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Purinescephalitis. While ara-A is not without certain toxic side effects, these are negligible when compared with those of previous antiviral nucleosides, particularly when the compound is given systemically. The approval of this drug for clinical use marked a great stride forward in antiviral chemotherapy
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Interferon and Its Inducersnovel insights into the regulation of gene expression in eukaryotic cells as well as into the pathophysiology of viral diseases. Thus, interferon research represents an important and rapidly advancing area of biomedical research today.
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Guanidineuanidine. Replication of Sindbis and Semliki Forest viruses of the . genus of the togavirus family (. 1970) and two plant viruses, tobacco necrosis (. 1968) and tobacco mosaic virus (TMV; . 1975) are sensitive to the inhibitor.
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Phosphonoacetic Acid in normal cells, and these functions serve to give the virus a selective advantage for replication. These virus-specific molecules can provide a target for selective attack on a virus-infected cell since they are absent in normal cells. The herpesviruses induce a new DNA polymerase in infected cell
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Natural Productslorey came the antibiotic age with all its glowing promise. The search for other natural substances was not as intense as that for synthetic antibacterial agents or antibiotics. Nevertheless, there were individuals who attempted to uncover antiviral agents in the plant, animal, or marine world. It i
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https://doi.org/10.1007/978-3-642-37688-7cephalitis. While ara-A is not without certain toxic side effects, these are negligible when compared with those of previous antiviral nucleosides, particularly when the compound is given systemically. The approval of this drug for clinical use marked a great stride forward in antiviral chemotherapy
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Black Holes in General Relativity,novel insights into the regulation of gene expression in eukaryotic cells as well as into the pathophysiology of viral diseases. Thus, interferon research represents an important and rapidly advancing area of biomedical research today.
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