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Titlebook: Chemotherapy; Volume 8 Cancer Chem K. Hellmann,T. A. Connors Book 1976 Plenum Press, New York 1976 cancer.chemotherapy.kinetics.pharmacokin

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A New Multipeptide Antitumour Drug,Investigations are reported concerning a new antiblastic drug, Peptichemio, a complex of 6 peptides of m-[di-(2-chloroethyl)- amino]-L-phenylalanine, with amino acids, physiologic or antagonistic of L-configuration. Chemical formula, pharmacological, biochemical, immunological and biological investigations are briefly outlined.
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Antitumour Activity of Benzofuroxan Derivatives,In a series of 4-Amino-7-Nitrobenzofuroxans, those with 4-piperazinyl substituents showed significant antitumour activity in mice.
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,Qualitätsmanagement im Gesundheitswesen,f cytotoxic drugs in cancer therapy. This method of conjugation provides for a high degree of drug substitution without significant loss of antibody activity and with no loss of water solubility. Suppression of tumour growth in vivo, and tests in vitro show greater effectiveness of the drug-carrier-
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,Begleitkonzepte des Qualitätsmanagements, concerned mostly the latter. It is known that the biological substrates of neoplastic processes are contained in DNA and RNA molecules of cancer cells. DNA and RNA are involved whatever the etiology of neoplasms: on the one hand, the possible modification of the genome by direct mutation of DNA or
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Qualitätsmanagement & Zertifizierung most active substances were actinomycin and an indomethacin-methylen-benzoic ester (IMB-1). It has been seen that IgM response is the most affected when drugs are administered in a short period of time and previously to the antigen.
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