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Titlebook: Chemotherapy; Volume 1 Clinical As J. D. Williams,A. M. Geddes Book 1976 Plenum Press, New York 1976 cancer.chemotherapy.kinetics.pharmacok

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,Antibiotic Prophylaxis — Yes or No? — Endocarditis,se has been widely used for over 25 years but its effectiveness has never been proved.(1) The basis of this practice is the observation that a small proportion of patients with endocarditis have a dental procedure before onset of the heart infection. However, among susceptible heart disease patients
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Recent Trends in the Epidemiology of Acute Meningitis,e meninges or brain. In an outbreak of meningococcal disease in Devon in 1972–73 there were 31 cases with six deaths, several of which occurred within hours of onset (Easton et al, 1974). One case, for example, was in a 10-month-old infant who had refused his feeds and was observed to be lethargic w
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The Current Status of Osteomyelitis,yelitis have been greatly reduced in recent decades, if this disease is unrecognized and untreated, the mortality rate is still about 20 percent. Equally important is the fact that rapid diagnosis and treatment are necessary to prevent progression to the disabling and frequently life-long chronic os
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Therapy of infections in acute leukemia,ten due to gram negative bacilli (., ., Klebsiella sp. ) and originate from sites such as lungs, pharynx, gastro-intestinal tract, perineal region and skin. Very often bacteremia is associated with these infections.
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Infection Prevention in Acute Myeloid Leukaemia: Oral Non-Absorbed Antibiotic Prophylaxis, than a quarter of these patients dying of infection before antineoplastic therapy has had an opportunity to induce remission (1–3). The effective prevention of infection in these patients should therefore improve the prognosis of the primary disease by permitting more prolonged and more intensive a
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Treatment of Neutropenia with Granulocyte Transfusions,locytopenia. Infection accounts for 80% of deaths occurring in such patients (1). There is a quantitative relationship between the level of circulating granulocytes and the frequency of infection (2), and the duration of granulocytopenia is also implicated in the rate of acquisition of infection (3)
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Parenteral Tobramycin and Cephalothin in the Treatment of Suspected Sepsis in Neutropenic Children,morphonuclear leukocytes/mm. of blood) with various underlying malignancies was undertaken. Twenty episodes of suspected sepsis in 19 febrile children with cancer were treated with parenteral tobramycin and cephalothin for a total of one to 80 days. Each was followed closely for renal, hepatic, bone
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