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Titlebook: Chemotherapeutic Strategy; Proceedings of the S D I Edwards,D R Hiscock Conference proceedings 1983 The Contributors 1983 cancer.internal m

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Antimicrobial agents affecting membrane function,ween the two sides of the membrane. Hence the membrane represents a region of chemical anisotrophy between two phases of different chemical composition. This means that the membrane experiences mechanical stress through differences in pressure across the membranes thickness and this sets up correspo
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Antibiotics as probes of ribosomal structure and function, ought to be possible to use antibiotics in order to arrive at structure-function relationships within the ribosomes. The working hypothesis underlying this approach is that ribosomal components involved in binding a given drug might also be involved in the process (es) inhibited by that drug. One p
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Chemotherapy of anaerobic bacteria,inal features of bacterial infection, although they are not commonly communicable from man to man. Botulism stands alone since it is almost always the result of a pure intoxication that develops in the absence of an infection. At the other extreme are diseases such as Vincent&;#x2019;s stomatitis an
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Quantitative structure-activity relationships (QSARs): Principle and practice, of two interrelated, but nonetheless distinct goals. On the one hand, the aim may be to collate data on the chemical structures and biological activities of existing compounds, with a view to identifying new compounds with improved therapeutic properties — the end being more important than the mean
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