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Titlebook: Chemokine Protocols; Amanda E. I. Proudfoot,Timothy N. C. Wells,Christi Book 2000 Humana Press 2000

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Book 2000afficking to the extravasation and tissue infiltration of leukocytes in response to inflammatory agents, tissue damage, and bacterial or viral infection. Chemokines exert their effects through a family of seven G-protein coupled transmembrane receptors. Worldwide interest in the chemokine field surg
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Queen Caroline and Sir William Gellning has resulted in an explosion in the number of new chemokines from 1995-1998. However, for studies of the protein, knowing the DNA sequence is only the first step. The chemokine must be generated and in its correctly processed and folded form, and then purified to homogeneity. Expression of the
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Svetlana G. Lukishova,Luke J. Bissellvel of homology at the primary sequence level, which can be as low as 20%, although it can also be as high as 90%, the three-dimensional structure of all the chemokines solved to date has shown that they have a superimposable monomeric fold. This fold is imposed on the family by the four cysteine mo
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