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Titlebook: Chemical Mutagens; Principles and Metho Frederick J. Serres Book 1983 Plenum Press, New York 1983 Antigen.base.kinetics.mutagenesis.researc

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书目名称Chemical Mutagens
副标题Principles and Metho
编辑Frederick J. Serres
视频video
图书封面Titlebook: Chemical Mutagens; Principles and Metho Frederick J. Serres Book 1983 Plenum Press, New York 1983 Antigen.base.kinetics.mutagenesis.researc
描述Volume 8 of Chemical Mutagens covers a wide range of topics in this continuously changing field. This volume includes chapters on the detection of genetic damage in mammalian sperm both at specific loci and over the entire genome. The discussion of in vitro techniques for working with mammalian cells covers not only specific locus assays but also cellular activation systems. Another chapter extensively discusses the need for a revised protocol for the micronucleus assay. Structure­ activity relationships are investigated in a chapter dealing with hair dye constituents. One of the most comprehensive chapters deals with problems associated with the detection of mutagenic effects in defined human populations. Finally, there is a detailed presentation of a comprehensive study tabulating the genetic bioassay data on some known or suspected human carcinogens. In keeping with our policy of publishing important legislation in the area of chemical mutagens, we have also included the Council of the European Communities Directive of 18 September 1979. Frederick J. de Serres Research Triangle Park, North Carolina vii Contents Chapter 1 Detection of Effects of Mutagens in Human Populations Geor
出版日期Book 1983
关键词Antigen; base; kinetics; mutagenesis; research; toxicity
版次1
doihttps://doi.org/10.1007/978-1-4613-3694-5
isbn_softcover978-1-4613-3696-9
isbn_ebook978-1-4613-3694-5
copyrightPlenum Press, New York 1983
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Conference proceedings‘‘‘‘‘‘‘‘ 2022e of chromosomal aberrations in carcinogenesis has been renewed, which may mean that clastogenicity will be a useful predictor of carcinogenicity. The involvement of chromosomal aberrations, and thus of clastogens, in carcinogenesis has been proposed by several authors. Cairns. has argued that becau
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The Bone Marrow Micronucleus Assay: Rationale for a Revised Protocol,e of chromosomal aberrations in carcinogenesis has been renewed, which may mean that clastogenicity will be a useful predictor of carcinogenicity. The involvement of chromosomal aberrations, and thus of clastogens, in carcinogenesis has been proposed by several authors. Cairns. has argued that becau
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ion of genetic damage in mammalian sperm both at specific loci and over the entire genome. The discussion of in vitro techniques for working with mammalian cells covers not only specific locus assays but also cellular activation systems. Another chapter extensively discusses the need for a revised p
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Danfeng Zhao,Xiangyu Song,Guiyang Lunthe consequences of genetic damage in somatic cells of exposed individuals. Among possible effects of somatic cell mutagenesis, the most notable is an increase in the incidence of cancer. The conceptual and experimental bases for associating cancer causation with somatic cell mutagenesis have recently been reviewed by Straus..
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