书目名称 | Chemical Mutagens | 副标题 | Principles and Metho | 编辑 | Frederick J. Serres | 视频video | | 图书封面 |  | 描述 | Volume 8 of Chemical Mutagens covers a wide range of topics in this continuously changing field. This volume includes chapters on the detection of genetic damage in mammalian sperm both at specific loci and over the entire genome. The discussion of in vitro techniques for working with mammalian cells covers not only specific locus assays but also cellular activation systems. Another chapter extensively discusses the need for a revised protocol for the micronucleus assay. Structure activity relationships are investigated in a chapter dealing with hair dye constituents. One of the most comprehensive chapters deals with problems associated with the detection of mutagenic effects in defined human populations. Finally, there is a detailed presentation of a comprehensive study tabulating the genetic bioassay data on some known or suspected human carcinogens. In keeping with our policy of publishing important legislation in the area of chemical mutagens, we have also included the Council of the European Communities Directive of 18 September 1979. Frederick J. de Serres Research Triangle Park, North Carolina vii Contents Chapter 1 Detection of Effects of Mutagens in Human Populations Geor | 出版日期 | Book 1983 | 关键词 | Antigen; base; kinetics; mutagenesis; research; toxicity | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4613-3694-5 | isbn_softcover | 978-1-4613-3696-9 | isbn_ebook | 978-1-4613-3694-5 | copyright | Plenum Press, New York 1983 |
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