Titlebook: Chemical Carcinogenesis 2; Modulating Factors Amedeo Columbano,Francesco Feo,Paolo Pani Book 1991 Springer Science+Business Media New York

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Control of Hepatocyte Growth by Positive and Negative Growth Regulators and Mitogenic Triggers: Implstic growth to regenerative growth. Liver regeneration after 2/3 partial hepatectomy (2/3 P.H.) is perhaps the best studied model for tissue regeneration. In recent years there have been major insights in the biochemical changes and changes in gene expression which occur during liver regeneration. S

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Growth Hormone-Regulated Expression of the c-, Gene during Sex-Differentiated Promotion of Rat Liverid (DCA) detectable levels of hepatic foci were observed only in males. one week after the PH performed at 5 weeks foci areas in males exihibited a 2-fold increase. Foci areas in liver from females and GH-treated males were detectable but 2–3 fold smaller than in ordinary males. The c-. expression i

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Delegates, Events, and Lambdas,of carcinogenic regimens. They constituite the most frequently occurring tumors in whole animal carcinogenesis bioassay. Liver tissue and its biochemistry have been extensively analyzed and a large data bank exists as a background for further studies. Several initiation — promotion protocols for liv

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Delegates, Events, and Lambdas,man T lymphocytes proliferation, 2) rat liver regeneration following partial hepatectomy, and 3) hyperplasia induced by the mitogen lead nitrate. In each case, a consistent increase in the level of poly(ADP-ribose) polymerase mRNA occurs before the start of DNA synthesis. A maximal level of the tran