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Titlebook: Chemical Biology; and Drug Discovery Marco F. Schmidt Textbook 2022 The Editor(s) (if applicable) and The Author(s), under exclusive licens

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Drug Developmenters (PwC) and Deloitte, the expenditure of the 12 largest pharmaceutical companies on drug development has been rising for years. In its report “From Vision to Decision Pharma 2020”, PwC reports that the average cost of a new drug is now more than four billion USD.
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Proteins as Drug Targetstors or enzymes. There is a mechanistic and a structural reason for this. The mechanistic reason is that proteins are the function carriers in the organism. The manipulation of their function has direct, i.e. clinical effects.
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