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Titlebook: Chemical Biology; and Drug Discovery Marco F. Schmidt Textbook 2022 The Editor(s) (if applicable) and The Author(s), under exclusive licens

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发表于 2025-3-21 19:48:51 | 显示全部楼层 |阅读模式
书目名称Chemical Biology
副标题and Drug Discovery
编辑Marco F. Schmidt
视频video
概述The only textbook of chemical biology & drug discovery.Navigator through the new discipline in the context of drug discovery.Must know for current and future pharmaceutical researchers
图书封面Titlebook: Chemical Biology; and Drug Discovery Marco F. Schmidt Textbook 2022 The Editor(s) (if applicable) and The Author(s), under exclusive licens
描述.The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be beyond the scope of a book). It gives the reader, through the specific selection of chemical biological techniques and concepts, the necessary tools to be able to develop new ways of thinking and thus new therapeutic options in the complex field of chemical biology and drug development. The stated aim of this book is to provide concrete solutions and inspiration to students, (post)graduate students, and experienced scientists at universities as well as in industry in their problems. .After an introduction to the problems addressed by chemical biology in drug discovery, the three levels of molecular biology dogma: DNA, RNA and proteins and their role as drug targets serve as the common thread of this book..This book is a translation of the original German 1.st. edition .Chemische Biologie .by Marco F. Schmidt, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2020. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done p
出版日期Textbook 2022
关键词Chemical Biology; Drug discovery; Chemical genetics; DNA; RNA; Pharmaceutical Research; Bioorganics; Biolog
版次1
doihttps://doi.org/10.1007/978-3-662-64412-6
isbn_softcover978-3-662-64411-9
isbn_ebook978-3-662-64412-6
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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From Genomic Research to Chemical Biologythat lead (via .) to the production of biologically active ribonucleic acids (RNA), which in turn code for 50,000 to 100,000 proteins (via .). On the other hand, the already approved drugs were examined.
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Gene Therapy and Genome Editingvention. Specifically, gene therapy drugs such as Zolgensma have been approved for the treatment of hereditary spinal muscular atrophy, and new genome editing techniques such as CRISPR-Cas have been developed. So, what is the difference between gene therapy and genome editing?
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Proteins as Drug Targetstors or enzymes. There is a mechanistic and a structural reason for this. The mechanistic reason is that proteins are the function carriers in the organism. The manipulation of their function has direct, i.e. clinical effects.
发表于 2025-3-23 02:30:19 | 显示全部楼层
Chemical Genomics: From Target Protein to Small Molecule Drugrse chemical genomics, related protein families are screened against chemical libraries. If an active agent is found, it is tested on cells. In most cases, forward and reverse chemical genomics experiments go hand in hand in order to clearly identify the drug target.
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