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Titlebook: Checkpoint Responses in Cancer Therapy; Wei Dai Book 2008 Humana Press 2008 DNA.apoptosis.biotechnology.cancer.cancer research.cancer ther

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Antiproliferation Inhibitors Targeting Aurora Kinases,and several small molecular ATP-site competitive inhibitors. The availability of several crystal structures with bound ADP, several drugs and peptide fragments from interacting proteins have provided a detailed insight of the active site, biological functions, rationale for the mode of binding of a
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Plks as Novel Targets for Cancer Drug Design,ors of various cell-cycle checkpoints. Deregulation of Plks occurs in a variety of human malignancies. During the past decade, much effort has been directed toward the discovery of novel chemical agents that target Plks specifically. We attempt to summarize recent developments in this field and disc
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MapReduce Details for Multimachine Clusters,and several small molecular ATP-site competitive inhibitors. The availability of several crystal structures with bound ADP, several drugs and peptide fragments from interacting proteins have provided a detailed insight of the active site, biological functions, rationale for the mode of binding of a
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Advanced and Alternate MapReduce Techniques,ors of various cell-cycle checkpoints. Deregulation of Plks occurs in a variety of human malignancies. During the past decade, much effort has been directed toward the discovery of novel chemical agents that target Plks specifically. We attempt to summarize recent developments in this field and disc
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