Titlebook: Checkpoint Controls and Targets in Cancer Therapy; Zahid H. Siddik Book 2009 Humana Press 2009 BRCA.DNA.cancer.cancer research.cancer ther

清晰

The Importance of p53 Signaling in the Response of Cells to Checkpoint Inhibitors

草本植物

Targeting p21-Dependent Pathways for Cell Death in Cancer Therapy

通知

p27Kip1 as a Biomarker and Target for Treatment of Cancer

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2196-9906 ncer therapy to provide an apoptotic stimulus when cellular damage induced by the therapeutic agent is detected by the sensor system. Therefore, it is not surprising that failure in pro-survival checkpoint resp978-1-61779-635-7978-1-60761-178-3Series ISSN 2196-9906 Series E-ISSN 2196-9914

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Free-Radical

Zahid H. SiddikBrings together experts, who are defining the field of checkpoints, and as such represents a unique collection of insightful contributions that will serve as an important resource for both the researc

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环形

Book 2009on, is an inherent characteristic of cancer. This loss may occur through aberration in any single component involved in signal transduction pathways that orchestrate checkpoint regulation, which may manifest through either a failure to activate the checkpoint or a failure to respond to the activated