Titlebook: Centromeres and Kinetochores; Discovering the Mole Ben E. Black Book 2017 Springer International Publishing AG 2017 centomeres.kinetochores

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https://doi.org/10.1007/978-3-658-00133-9y and function. To illustrate the transcriptional landscape of centromeres across eukaryotes, we focus this review on how transcripts interact with centromere proteins, when in the cell cycle centromeric transcription occurs, and what types of sequences are being transcribed. Utilizing data from bro

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Use of Mass Spectrometry to Study the Centromere and Kinetochoreexpression cloning methods, which allowed antibodies to lead to cDNA clones. Next, functional screens for kinetochore proteins were made possible by the isolation of yeast centromeric DNAs. Ultimately, the completion of genome sequences for humans and model organisms permitted the coupling of bioche

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Centrochromatin of Fungiment options against fungal infection, and biotechnologies based on fungi. This review summarizes the current knowledge of fungal centromeres and centrochromatin, including an outlook for future research.

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Evolutionary Lessons from Species with Unique Kinetochoreslar localization of kinetochores has changed from the nucleoplasm to the nuclear membrane. Finally, we speculate on the organization of the chromosome segregation machinery in an early eukaryotic ancestor to gain insights into fundamental principles of the chromosome segregation machinery, which are

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Artificial Chromosomes and Strategies to Initiate Epigenetic Centromere Establishmentenome to dissect the role of many centromere-associated proteins and chromatin modifiers for centromere inheritance and function. Together, these studies showed that chromatin context matters, particularly proximity to heterochromatin or repetitive DNA sequences. Moreover, despite the important cont