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Titlebook: Centromeres and Kinetochores; Discovering the Mole Ben E. Black Book 2017 Springer International Publishing AG 2017 centomeres.kinetochores

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Organisation der Forschungsuniversitätthat divide asymmetrically to generate gonial pre-cursors, which are amplified in number by mitotic divisions, undergo meiosis and eventually differentiate into mature gametes (haploid eggs and sperm). Information transmitted with gametes is inherited by offspring, and potentially by subsequent gene
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https://doi.org/10.1007/978-3-642-99771-6expression cloning methods, which allowed antibodies to lead to cDNA clones. Next, functional screens for kinetochore proteins were made possible by the isolation of yeast centromeric DNAs. Ultimately, the completion of genome sequences for humans and model organisms permitted the coupling of bioche
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Umweltbezogene Unternehmungsstrategienlar localization of kinetochores has changed from the nucleoplasm to the nuclear membrane. Finally, we speculate on the organization of the chromosome segregation machinery in an early eukaryotic ancestor to gain insights into fundamental principles of the chromosome segregation machinery, which are
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Kerstin Cuhls,Terutaka Kuwaharaly in early G1, into pre-existing chromatin, and several additional chromatin-associated complexes regulate CENP-A nucleosome deposition and stability. Here we review the current knowledge on how new CENP-A nucleosomes are assembled selectively at the existing centromere in different species and how
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