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Titlebook: Central Nervous System Tumors; Diagnostic Pathology César R. Lacruz Book 2023 The Editor(s) (if applicable) and The Author(s), under exclus

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Pineal Tumors,equency, these neoplasms often pose a diagnostic dilemma due to the diversity of pathologic types. Most pineal region neoplasms belong to the germ cell group, mainly . (over a half of pineal tumors) and ., followed by . (pineocytoma, pineal parenchymal tumor of intermediate differentiation, pineobla
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Cranial and Paraspinal Nerve Tumors,ast majority of which are schwannomas. Craniospinal nerve sheath tumors may be encountered either sporadically or as a part of a variety of tumor predisposition syndromes, including neurofibromatosis type 1, neurofibromatosis type 2, schwannomatosis, and Carney complex. This chapter reviews the clin
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Mesenchymal, Non-meningothelial Tumors,nting the homologous of neoplasms encountered far more frequently in the somatic soft tissues or bones. Thus, the 2021 WHO classification of CNS tumors has strived to align its terminology with their counterparts in the WHO Blue Book on Bone and Soft Tissue Tumors. Furthermore, three recently descri
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Primary CNS Melanocytic Neoplasms,lanocytes. Lesions can manifest as diffuse disseminations within the subarachnoid space (meningeal melanocytosis and meningeal melanomatosis) or as solid masses (meningeal melanocytoma and meningeal melanoma). Meningeal melanocytomas with increased mitotic activity or invasion of the CNS parenchyma
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Primary CNS Lymphomas,eal locations. Thus, by definition, there is no co-existing systemic disease at the time of diagnosis, distinguishing these lesions from CNS involvement arising from systemic .s (.s). The 2021 WHO classification scheme includes the entities listed in Table .. Despite impressive advances in the under
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Histiocytic Tumors of the CNS,s. They represent a heterogeneous group of tumors composed primarily of histiocytes that are totally homologous to those of an extra-neuraxial location. Histiocytic tumors can be divided into two groups: Langerhans cell histiocytosis (LCH) and non-LCH (a group of disorders defined by the accumulatio
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Germ Cell Tumors of the CNS,and have a marked predilection for males (more than twice as females). In the Europe and USA, the frequency is not high, representing approximately 0.5% of primary intracranial tumors and 3% of those affecting children. However, these figures are quadruple in eastern Asia (Taiwan, Japan, China, and
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