书目名称 | Central Nervous System Tissue Engineering | 副标题 | Current Consideratio | 编辑 | Ashley E. Wilkinson,Aleesha M. McCormick,Nic D. Le | 视频video | | 丛书名称 | Synthesis Lectures on Tissue Engineering | 图书封面 |  | 描述 | Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person‘s quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell so | 出版日期 | Book 2012 | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-02582-2 | isbn_softcover | 978-3-031-01454-3 | isbn_ebook | 978-3-031-02582-2Series ISSN 1944-0316 Series E-ISSN 1944-0308 | issn_series | 1944-0316 | copyright | Springer Nature Switzerland AG 2012 |
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