Titlebook: Central Functions of the Ghrelin Receptor; Jeanelle Portelli,Ilse Smolders Book 2014 Springer Science+Business Media New York 2014 addicto

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Ghrelin Receptor Antagonism as a Potential Therapeutic Target for Alcohol Use Disorders: A Preclinicdysfunction in these reward systems underlies development of addictive behaviours such as alcohol use disorder. By elucidating the complex neurobiological mechanisms involved in the drug-induced activation of the mesolimbic dopamine system, novel treatment strategies can be identified. Recent work h

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Clinical Research on the Ghrelin Axis and Alcohol Consumptionelin receptor) and regulates a number of physiological processes including energy homeostasis, appetite, gut motility, anxiety, sleep, cardiovascular functions, and inflammation. In addition, preclinical studies demonstrate ghrelin’s involvement in reward signaling by its actions in the mesolimbic d

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Ghrelin and Sleep Regulatione circadian phase is favorable for sleep. Growing body of evidence indicates, however, that in addition to these factors, other signals from the external and internal environment also play a key role in sleep regulation. Changes in metabolic environment, such as positive and negative energy balance,

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Ghrelin and Memoryesides its role in metabolic processes, accumulating evidence suggests that ghrelin also plays an important role in the cognitive aspects of energy homeostasis, in particular learning and memory. Several studies in rodents confirm enhancing effects of ghrelin on fear learning, object recognition and

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Ghrelin Receptors and Epilepsypileptic medications that are currently available. As such, there is a great need for new, more effective drugs for the treatment of epilepsy. Drugs that target neuropeptide systems in the brain show great promise for preventing seizures and epilepsy. Little is currently known about the ghrelin rece

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Ghrelin Plays a Role in Various Physiological and Pathophysiological Brain Functionsth hormone secretagogue receptor (ghrelin receptor) may promote anxious behaviours under non-stressed conditions, and attenuate anxiety under conditions of stress. Dysregulation of the ghrelin system therefore has significant consequences for stress-related mood disorders such as anxiety and depress

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J. P. Hulsbergen Henning,M. J. C. van Gemertlin-induced feeding, indicating that the vagal afferent system is important to convey orexigenic ghrelin signals to the brain. In this chapter, we mention the role of the vagal afferent system for feeding regulation by gastrointestinal hormones and show the functional linkage in feeding between peripheral ghrelin and the vagal afferent system.

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