Titlebook: Centenarians; An Example of Positi Calogero Caruso Book 2019 Springer Nature Switzerland AG 2019 Aging.Longevity.Phenotype.Genetics.Epigene

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Epigenetics and Ageing,e expression and the activity of genes (Armstrong, Epigenetics, Garland Science, New York, 2013; Pinel et al., BioSocieties 13:276–303, 2018). In fact, DNA methylation and histone modification, that are covalent and non-covalent modifications of DNA and histone proteins, alter DNA accessibility and

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Lifestyle Choices, Psychological Stress and Their Impact on Ageing: The Role of Telomeres,ing with increasing age is a part of the normal ageing process. However, factors such as inflammation, oxidative stress and other genotoxic stressors may also increase the rate of telomere attrition, leading to telomere dysfunction-mediated cellular senescence and accelerating the ageing process. On

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