Titlebook: Centenarians; An Example of Positi Calogero Caruso Book 2019 Springer Nature Switzerland AG 2019 Aging.Longevity.Phenotype.Genetics.Epigene

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Epigenetics and Ageing,en considered as a bridge between genome and environment in the definition of phenotype (Norouzitallab et al., Sci Total Environ 647:1281–1293, 2018). Many evidences have suggested in the last decade that ageing, which is deeply influenced by genetics, environment and their interaction, may be influ

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Lifestyle Choices, Psychological Stress and Their Impact on Ageing: The Role of Telomeres,lomere shortening, likely because they increase DNA damage through oxidative stress. Recently, studies have identified lifestyle factors that can potentially protect telomeres. For example, people who lead a healthy lifestyle by increasing their physical activity, practising meditation, adhering to

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,Lifespan and Healthspan Extension by Nutraceuticals: An Overview,mental model organisms. We also highlight the potential ability of nutraceuticals to extend the healthy years in humans, encouraging more in-depth and well-controlled clinical and epidemiological studies to better define the potential healthspan-promoting effects of these compounds.

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Genetic Signatures of Centenarians,me ages. The challenge, since the beginning of the 1990s, was the identification of the genetic variants that predispose these individuals to avoid diseases of ageing and live long and healthy lives. Genetic approaches (study design) were adopted based on the available platforms. Indeed, entrepreneu