| 书目名称 | Cellular and Molecular Toxicology of Nanoparticles | | 编辑 | Quaiser Saquib,Mohammad Faisal,Abdulrahman A. Alat | | 视频video | | | 概述 | A unique account of the effects on the transcriptome following exposure to nanoparticles.A compilation of the latest findings to address the query on the potential mechanisms of nanoparticle induced c | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | .This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types...Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs | | 出版日期 | Book 2018 | | 关键词 | Nanotoxicity; Nanoparticles; Genotoxicity; Cell Death; Apoptosis; Transciptomics | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-72041-8 | | isbn_softcover | 978-3-030-10150-3 | | isbn_ebook | 978-3-319-72041-8Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 18:27:17
