Titlebook: Cellular Osmolytes; From Chaperoning Pro Laishram Rajendrakumar Singh,Tanveer Ali Dar Book 20171st edition Springer Nature Singapore Pte Lt

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Insertion and Extrusion Reactionsfect of denaturants under both . and . conditions. In fact, organisms use a large amount of different varieties of osmolytes as an adaptation to the environment where they reside. In this chapter, an up-to-date knowledge of the roles of organic osmolytes in regulating the cell volume is being discus

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Impact of Osmolytes in Conformational Modulation of Protein and Its Applications in Biotechnology,folding, increases their stability and inhibit aggregation. Osmolytes are also known as chemical chaperones. Hence, it may be therapeutically used for several misfolding diseases. The present chapter discusses the impact of these small molecules on folding of proteins and their stabilization.

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Akira Hasegawa,Masayuki Matsumotoxact mechanism by virtue of which these osmolytes are able to impart stability to the proteins. It also elucidates on the application of these osmolytes in treatment of various diseases and as possible drugs from the pharmaceutical point of view.

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Osmolyte System and Its Biological Significance,xact mechanism by virtue of which these osmolytes are able to impart stability to the proteins. It also elucidates on the application of these osmolytes in treatment of various diseases and as possible drugs from the pharmaceutical point of view.

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Clinical Implications of Osmolytes in Various Human Diseases,associated with the protein quality control system. In this chapter we have systematically reviewed the clinical implications of the osmolytes for human diseases and discussed the advances made on some particular diseases wherein osmolytes’ therapeutic role has been extensively investigated. Future clinical perspectives have also been described.

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