| 书目名称 | Cellular Osmolytes |
| 副标题 | From Chaperoning Pro |
| 编辑 | Laishram Rajendrakumar Singh,Tanveer Ali Dar |
| 视频video | |
| 概述 | Provides comprehensive understanding of complex osmolyte-protein interactions with extensive and updated mechanistic insights.Brings forth insights for use of osmolytes as therapeutic strategy for var |
| 图书封面 |  |
| 描述 | .This book provides essential information on improving protein folding/stability, which is a result of the balance between the intra-molecular interactions of protein functional groups and their interactions with the solvent environment. The protein folding solvent environment mainly consists of salts, small molecule compounds, metabolites, molecular chaperones and other chemical species. Therefore, subtle change in the composition of the environment will alter the protein folding process. The importance of the solvent environment in protein folding is precisely due to the fact that various disease-causing proteopathies can be reversed by manipulating the solvent environment of the malfolded proteins. Hostile environmental stresses represent one of the basic causes of such challenges in protein folding or misfolding. Since cells commonly encounter extreme environmental fluctuations, it is crucial that they equip themselves with strategies to circumvent the hostile environmental conditions. Nature has developed many strategies to ensure that the complex and challenging protein folding reaction occurs with adequate efficiency and fidelity for the success of the organism. Among the st |
| 出版日期 | Book 20171st edition |
| 关键词 | Osmolytes; Chemical chaperones; Protein folding; Protein stability; Protein misfolding; Stress; Protein-Li |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-981-10-3707-8 |
| isbn_softcover | 978-981-10-9947-2 |
| isbn_ebook | 978-981-10-3707-8 |
| copyright | Springer Nature Singapore Pte Ltd. 2017 |
发表于 2025-3-21 19:33:29
