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Titlebook: Cellular Drug Delivery; Principles and Pract D. Robert Lu,Svein Øie Book 2004 Springer Science+Business Media New York 2004 biology.cancer.

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https://doi.org/10.1007/978-3-322-97216-3 established antiviral immunity in many patients and the rapid induction of an adaptive immune response in naïve patients continues to block many attempts to introduce DNA by viral vectors. Nonviral delivery strategies avoid the problems of viral-coat proteins, but encountered new challenges of low
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Der lange Weg vom DDR- zum Bundesbürgerntry of nutrients; facilitate uptake and release of hormones, neurotransmitters, and various signaling molecules; participate in transfer of nucleic acids across the cell membrane; and participate in secretion of proteins, lipids, and carbohydrates into and beyond the cytoplasmic membrane. These mem
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Zur Mentalität der ostdeutschen Jugend of structurally unrelated large lipophilic compounds from the cell, providing what is often known as multiple drug resistance (MDR) .. MDR is characterized by active efflux or pumping of xenobiotics and pharmaceuticals via transmembrane proteins acting as hydrophobic “vacuum cleaners” .,.. The MDR1
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Der lange Weg vom DDR- zum Bundesbürgerrally the case, even when the site of drug action is beyond the gastrointestinal tract (GI), requiring the drug to be systemically available. For systemic drug availability, drug dosing via the oral route requires the drug to exhibit sufficient gastrointestinal absorption. Two components of drug abs
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https://doi.org/10.1007/978-3-322-97626-0lar complexes or organelles within a cell while avoiding drug loading in nontargeted cells. Targeted delivery of drugs to specific cells involves the specific interactions between drugs or drug carriers and the cell-surface proteins through ligand—receptor interactions or antigen—antibody interactio
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https://doi.org/10.1007/978-3-322-97664-2currently considered incurable, e.g., cancer, cystic fibrosis (CF), severe combined immunodeficiency (SCID), and acquired immune deficiency syndrome (AIDS) .. Considering the tremendous promise of DNA-delivery technology, in addition to the extensive genetic information now available from the Human
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