Titlebook: Cellular Ageing and Replicative Senescence; Suresh I.S. Rattan,Leonard Hayflick Book 2016 The Editor(s) (if applicable) and The Author(s),

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2199-9007 r in cell proliferation regulation.Explains usage of the celThis book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer. .Cellular Ageing and Replicativ

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Cell Cycle Checkpoints and Senescencees, both as molecular sensors and regulators in this process. Aim of the present chapter is to sketch a brief understanding on how cellular senescence is regulated by major tumour suppressor and cell cycle checkpoint proteins as well as by some emerging molecules.

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Who Takes Part in Online Citizen Science?, mechanisms through which mitochondrial ROS promotes senescence. In this context, we will highlight how mitochondrial ROS serves an initiating upstream, or sustaining downstream, role in the induction of senescence. We will also discuss potential interventions to alleviate mitochondrial ROS and delay cellular senescence.

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