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Titlebook: Cell Impairment in Aging and Development; Vincent J. Cristofalo,Emma Holečková Book 1975 The Editor(s) (if applicable) and The Author(s),

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The Effect of Age on Mitochondrial Ultrastructure and Enzymes,ll mitochondria were enlarged and rounded with a light “foamy”, vacuolated matrix, short cristae and a loss of dense granules. Quantitative studies showed a 60% increase in the mean size and an increased proportion of larger mitochondria in intact 30 month-old perfused livers. Endothelial and Kupffe
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Creatinephosphokinase in Human Diploid Cell Lines, in various neuromuscular diseases. In some of them, as in Duchenne myopathy, its activity is significantly increased (1). In human tissues, the highest activity was found in muscle, heart and brain. Very low activity was detected in uterus, gall bladder, pylorus, adrenal and thyroid glands (2) and
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Enzymatic Differences between Short-Lived and Long-Lived Drosophila Strains,, among others of the acid phosphatase EC 3.1.3.2. On the other hand the activity of alkaline phosphatase,EC 3.1.3.1. does not change in ageing diploid cells (1), although its activity increased in hydrocortisone-treated diploid cells with prolonged lifespan (2). However, the activity of this enzyme
发表于 2025-3-31 03:41:59 | 显示全部楼层
Cell Ageing in the Intestinal Tract,an be tested by comparing cells from the crypts and different levels on the villus in the small intestine. We know from the work of Lesher’s group (1) that the transit time from crypt base to villus tip in the mouse jejunum is just over 50 hr in both 1-year-old and 2 1/2-year-old animals, of which a
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Characteristics of Proliferative Cells from Young, Old, and Transformed WI 38 Cultures, of this non-dividing subpopulation may be monitored by autoradiographic techniques, and these data have predictive value in assessing the amount of potential lifespan completed by a particular cell population during its sojourn in culture.
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Cell Ageing in the Intestinal Tract,bout 6 hr is spent in the crypt. There is therefore no difference in the post-mitotic age of cells at a similar level in the villus in adult and aged mice, although they are derived from stem cells of different ages.
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Springer Series in Optical Sciences of this non-dividing subpopulation may be monitored by autoradiographic techniques, and these data have predictive value in assessing the amount of potential lifespan completed by a particular cell population during its sojourn in culture.
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