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Titlebook: Cell Fusion in Health and Disease; I: Cell Fusion in He Thomas Dittmar,Kurt S. Zänker Book 2011 The Editor(s) (if applicable) and The Autho

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https://doi.org/10.1007/978-981-97-1627-2ion, and enzyme release. The universal molecular mechanism of membrane fusion involves Ca., and the assembly of a specialized set of proteins present in the opposing membrane bilayers. For example in cell secretion, target membrane proteins at the cell plasma membrane SNAP-25 and syntaxin termed t-S
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General Issues Concerning Life Imprisonment,ommon. These steps include programming fusion-competent status, chemotaxis, membrane adhesion, membrane fusion, and post-fusion resetting. Recent advances in the field start to reveal the molecules involved in each step. This review focuses on some key molecules and cellular events of cell fusion in
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General Issues Concerning Life Imprisonment,s organized in two distinct layers, the multinucleated syncytiotrophoblast directly facing maternal blood and a second layer of mononucleated cytotrophoblasts. During pregnancy single cytotrophoblasts continuously fuse with the overlying syncytiotrophoblast to preserve this end-differentiated layer
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General Issues Concerning Life Imprisonment,nce of distinct morphological types of giant cells, the signaling pathways that induce their formation, the molecular mechanism(s) of macrophage fusion, nor the significance of macrophage multinucleation at chronic inflammatory sites are well understood. Our efforts have been focused on these unknow
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General Issues Concerning Life Imprisonment,. Whereas the cellular steps leading to the formation of a multinucleated myofiber are conserved in several model organisms, the molecular regulatory factors may vary. Understanding the common and divergent mechanisms regulating myoblast fusion in . (fruit fly), . (zebrafish) and . (mouse) provides
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Mohammad Danish,Merajul Islam Robaby. The discovery that bone marrow stem cells fuse with several cell types, under normal condition or after an injury, introduces new possibilities in regenerative medicine and genetic repair. Cell fusion has been shown to be implicated in regeneration, and the complementation of recessive mutations
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https://doi.org/10.1007/978-981-97-2045-3 and tumor cells. The resultant hybrid uses the specialized antigen presentation properties supplied by the dendritic cell fusion partner to present tumor antigens, both known and yet undefined, to the immune system. This chapter critically examines the scientific foundation of this approach mainly
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